LoxP sites were inserted to flank exon 2. An frt-flanked neomycin selection cassette inserted in intron 3 was removed via FLP-mediated recombination in the germline. (J:246324)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count