Exon 13, which encodes most of the KDM2B ZF-CxxC domain and is shared by both the long and short form of the protein, was flanked by loxP sites. A neomycin resistant gene cassette flanked with FRT sites was removed in ES cells prior to the generation of mutant mice. (J:296282)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count