LoxP sites and a loxP-flanked neomycin selection cassette was inserted to flank exon 2. Cre-mediated recombination in ES cells resulted in the germline resulted in the deletion of exon2 and the selection cassette. (J:321351)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count