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The single coding exon was flanked by loxP sites. An EGFP reporter cassette, was inserted downstream of the floxed coding exon. Upon Cre-mediated recombination, the coding exon of the gene is replaced by the EGFP minigene that fails to express the endogenous encoded protein. A, frt-flanked neomycin resistance cassette was eliminated in vivo by crossing to a FLPe deleter strain. (J:251437)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
