A targeting vector was designed to insert a double hemagglutinin (HA) tag into the 3'end of exon 6 of the gene. A loxP site, followed by a frt-flanked neomycin resistance cassette, was inserted upstream of exon 6, and a second loxP site was inserted downstream. Cre and FLP-mediated recombination in the germline removed the neomycin resistance cassette and the HA-tagged exon 6. (J:272910)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6)F1
Targeted
Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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