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A PGK-neomycin selection cassette flanked by loxP sites replaced exons 3 and 4 and part of exon 5. The neomycin cassette was removed via flp-mediated recombination. RT-PCR conformed the complete loss of transcript and immunofluorescent labeling of the kidney and small intestine confirmed the absence of protein. In addition, protein expression of NKRP1G, which lies in apposition to this gene, is not affected. (J:322835)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
