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This transgene consists of the human keratin 18 cDNA containing an arginine to cysteine substitution at amino acid 89 in exon 1. Three lines were generated; F22, F30, and F50. The transgene copy number for line F50 is 18. The relative protein ratio of endogenous mouse Krt18 to over-expressed human KRT18 is 1:1. (J:241700)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
