The targeting vector inserted a loxP site upstream of exon 20 and a neomycin resistance cassette flanked by FRT- and loxP site downstream of exon 21. Flp-mediated recombination removed the neomycin resistance cassette and left exons 20 and 21 floxed. (J:286480)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count