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This trasngene expresses m157, which is the murine cytomegalovirus (MCMV)encoded ligand for the mouse Klra8 (Ly49H) NK cell activation receptor, under the control of a ubiquitous CMV promoter. The m157 ORF encodes a deduced 329-aa polypeptide. m157 contains a potential N-terminal 21-aa signal peptide, and an ectodomain with five potential sites for N-linked glycosylation. However, a putative hydrophobic transmembrane domain is interrupted by a stop codon. No line numbers were given. (J:138607)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
