The targeting construct introduced upstream of exon 2 a loxP site and downstream of exon 2 an inverted FRT-flanked tdTomato reporter gene and human diphtheria toxin receptor (HBEGF) with a single loxP site. Cre-mediated recombination is required to achieved expression of the construct. (J:322359)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count