Exons 3 was flanked by loxP sites and an FRT-flanked neomycin selection cassette was inserted downstream of the floxed exon. Flp-mediated recombination deleted the selection cassette leaving exon 3 floxed. (J:281839)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count