Zinc-finger nucleases and a targeting donor RNA were used to insert loxP sites surrounding exon 2 and an FRT flanked neo cassette downstream of the second loxP site. Flp mediated recombination removed the neo cassette. (J:322582)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count