Using sgRNAs (targeting GTGTCGTCTATGGAACGGAT and GCCCATTAGAAGGTGCTTTA) and an ssODN template with CRISPR/Cas9 technology, cysteine codon 362 (TGC) was changed to serine (TCC) (p.C362S). This mutation allows the residue to be phosphorylated in the encoded peptide. (J:297236)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count