The targeting construct introduced a floxed neomycin resistance cassette upstream of exon 2 and an additional loxP site downstream of exon 3. Cre-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:266026)
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The targeting construct introduced a floxed neomycin resistance cassette upstream of exon 2 and an additional loxP site downstream of exon 3. Cre-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:266026)