Log In|Sign Up
EN
CRISPR-targeting deleted exon 6. The deletion removed a serine (S208) important for the catalytic function of ABHD2, and resulted in a frameshift and a premature stop codon in exon 7. Western blotting and IHC analysis confirmed the complete absence of protein expression in the ovaries of homozygous mutant mice. (J:322075)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
