The targeting cassette floxed exons 3 and 4 and inserted an FRT-flanked neomycin resistance cassette proximal to the exon 3 loxP site. Flp-mediated recombination removed the selection cassette. (J:321947)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count