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EN
Two loxP sites were introduced flanking exons 2 to 8 and another set of exons 2-8 containing a T to A change resulting in a cysteine to serine substitution at amino acid 247 (C247S) in exon 5 was incorporated after the second loxP site. In addition, a neomycin selection cassette flanked by self-deletion anchor sites was inserted upstream of the second loxP site and was removed in germ cells. (J:322003)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
