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The targeting construct inserted into exon 1 of the mouse gene after the translation initiation codon a floxed transgene containing the human cDNA of isoform 1N4R mutated at P301L with a STOP codon and V5 epitope tag. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette at the 5' end of the transgene. (J:321949)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
