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An attenuated diphtheria toxin A gene and loxP-flanked neo cassette were inserted immediately downstream of the start methionine codon replacing the coding region through part of exon 9. Expression of this allele results in the ablation of intrinsically photosensitive retinal ganglion cells. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:134780)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
