CRISPR/Cas9 technology generated T to A change at position 323 resulting in a valine to glutamate substitution at residue 108 (V108E), generating a high SpTx1-sensitive mutant allele. SpTx1 is a Kir6.2-pore blocking venom toxin. (J:321749)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count