CRISPR/Cas9 technology generated T to A change at position 323 resulting in a valine to glutamate substitution at residue 108 (V108E), generating a high SpTx1-sensitive mutant allele. SpTx1 is a Kir6.2-pore blocking venom toxin. (J:321749)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
FVB/N
Endonuclease-mediated
Single point
--
1
14
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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