A vector containing the following elements was inserted into intron 1: the CAG promoter, a loxP site, the neomycin resistance gene, a STOP cassette, a second loxP site, a human PANX1 cDNA with C-terminal FLAG tag sequence, an IRES, the EGFP reporter gene and poly(A) signal sequence. The PANX1 and EGFP genes will only be expressed after cre-mediated deletion of the neo-STOP cassette. (J:314437)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
Insertion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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