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Using CRISPR/Cas9-mediated genome editing, 53 bp in the exon 2 of the Ccl28 gene was deleted causing a reading frame shift and the early translational termination. Quantitative real-time PCR (qRT-PCR) analysis of CCL28 mRNA derived from lung, colon, and salivary glands confirms the absence of mRNA in the homozygous mice. (J:321185)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
