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The targeting construct floxed inserted into the first coding exon a floxed neomycin resistance and STOP cassette and replaced exon 3 was a modified one containing a GCC to TAC mutation that results in the amino acid substitution alanine with tyrosine at position 226 (A226Y). (J:321029)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
