The V-gene segment of the immunoglobulin heavy chain of the immunoglobulin heavy chain of the mouse B-cell hybridoma VI41 secreting a VSV-neutralizing antibody was cloned into an expression vector encoding the mouse mu-chain of allotype a. Transgenic mice express the transgenic mu-chain of the allotype a; endogenous IgM of the allotype b and immunoglobulins of other subclasses were not detected in their serum. (J:44933)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
--
Insertion
--
--
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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