A loxP site was introduced approximately 2 kb upstream of the 5' untranslated region and an FRT-flanked neomycin resistance gene and second loxP site were inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette leaving exons 1 and 2 floxed. (J:320789)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count