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CRISPR-targeting of exon 2 deleted the open reading frame. The "P2" parental line, containing the larger deletion, was selected from two founder lines with similar incisor and fertility defects for further characterization. qPCR analysis confirmed the complete absence of mRNA expression in ovary and lung tissue from homozygous mutant mice. (J:318711)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
