The targeting construct obtained from Helmholtz Zentrum Muenchen GmbH inserted upstream of exon 5 an FRT site, splice acceptor, IRES sequence, lacZ reporter gene, polyadenylation sequence, loxP site, neomycin resistance cassette, FRT site, and loxP site. An additional loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the reporter gene and selection cassette. (J:318712)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S2/SvPas x C57BL/6NSlc)F1-Tg(CAG-EGFP,Acr-EGFP)2Osb
Targeted
Insertion
--
1
3
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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