CRISPR-targeting produced a fusion between the endogenous gene and the human sequence within the BiTE binding region (Q22-T48). A floxed neomycin resistance cassette was inserted downstream of exon 2. (J:318716)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count