CRISPR/cas9 genome editing used CrRNAs to target upstream (CCTTCAGCAGGTACTATCCA; CCCTTCAGCAGGTACTATCC) and downstream (CTGGCCATGCTCAGGCCCTA; ATGCTCAGGCCCTAGGGATG) regions of exon 2 designed to create a floxed conditional line, nstead created a 1156 bp deletion incorporating exon 2 (CCCTCCAGCTTCTAGTGGCCCTGG/del1156/AGGTACAGTCCCTCTCTCCTGCTCTCTTAGCAGGACAA). (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count