Log In|Sign Up
EN
CRISPR/cas9 genome editing used guide RNAs (AGCCTTTGAGGCCAAACTAC, CAAACTACAGGAAATTGAAA and TATTCGTTCATGATCTTGAA) originally designed to introduce an H871Q mutation. DNA sequencing of the targeted region identified a 43 bp deletion (indel mutation) in exon 2. (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
