CRISPR/cas9 genome editing used crRNAs to insert loxP sites upstream (GCTCATTCCCATAATGAACC; CCCCCCGCCAGGTTCATTAT) and downstream (TAACAGTAACCACACCAACA; GTTTCTCTGCCATGTTGGTG) regions of exon 5 (ENSEMBL Transcript ID: ENSMUSE00001222215). (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count