A loxP site was inserted about 83 bp upstream of exon 3 and a loxP site and an FRT-flanked neomycin selection cassette was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette, leaving exon 3 floxed. (J:319555)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count