The targeting construct introduced a loxP- and FRT-flanked neomycin resistance cassette into intron 7 and a single loxP site upstream of exon 6. Flp-mediated recombination removed the selection cassette and left exon 6 floxed. (J:319442)
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The targeting construct introduced a loxP- and FRT-flanked neomycin resistance cassette into intron 7 and a single loxP site upstream of exon 6. Flp-mediated recombination removed the selection cassette and left exon 6 floxed. (J:319442)