The targeting construct inserted the point mutation C to T generating the amino acid substitution of arginine with tryptophan at position 235 (R235W). Flp-mediated recombination removed the selection cassette. (J:319363)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count