The targeting construct inserted into the locus a CAG ubiquitous promoter, floxed stop cassette, the chimeric antisense for human ASTN2 and PAPPA. The final allele lacks a self-excising neomycin resistance cassette. (J:318677)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count