Using the dual guide CRISPR-Cas9 genome modification strategy the Lgr6, the deletion of exons 15 and 16 of the Lgr6 gene resulted in a frameshift and a nonsense transcript. (J:318857)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count