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CRISPR/cas9 genome editing is used to insert loxP sites flanking exon 2. The following guide RNAs were selected to target upstream [AAGTGTCCCCAAATATTGTC] and downstream [GCACCTAGCACATTGCCATG] of exon 2. Rag1 transcript Rag1-201 was used as reference for the exon numbering and the guide/donor sequences. (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
