This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CCACAAATACCACTCAACTG and CTTCTCTTAGGTGTCAGAAG, which resulted in a 392 bp deletion beginning at Chromosome 7 position 16,368,468 bp and ending after 16,368,859 bp (mm10). This mutation deletes ENSMUSE00000433769 (exon 4) and 249 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 132 and early truncation 16 amino acids later. (J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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