Exon 2 was flanked by loxP sites. An FRT-flanked neomycin selection cassette was inserted upstream of exon 2 and was removed via flp-mediated recombination leaving exon 2 floxed. (J:255335)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count