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A single loxP site was introduced into intron 3 and a floxed PGK-neo cassette was introduced downstream of exon 7 through homologous recombination. Cre-mediated recombination removed the loxP-flanked neomycin cassette leaving a single loxP site downstream of exon 7. Selected mice retained loxP sites flanking exons 4-7. (J:81015)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
