The targeting vector was designed to insert a loxP and an FRT flanked pGK-Neomycine-polyA cassette upstream of the exon1 of the Loxl1 genomic sequence and insert another loxP after the exon1. The neo cassette was removed by Flp recombinase. (J:317721)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count