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CRISPR-targeting of exon 3 produced three deletion alleles: a 32-bp deletion, a 19-bp deletion, and a 34-bp deletion. The pound symbol is used because the lines are pooled. Western blot analysis confirmed absence of protein in E18.5 embryos, while the expression levels of other Dyrk family members are unchanged. (J:312414)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
