The targeting vector is designed to insert a loxP site upstream of exon 3, and a PGK-neo cassette followed by a second loxP site just downstream of exon 3. (J:91531)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count