The targeting vector is designed to insert a loxP- and FRT-flanked neomycin resistance cassette upstream of exon 3 and a third loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neomycin cassette. (J:101977)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count