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CRISPR-targeting produced the amino acid substitution of glycine to arginine at position 13 (G13A). A floxed stop cassette in intron 1 prevents expression unless removed by cre-mediated recombination. A silent G to A mutation occurred in the third nucleotide of codon 15. (J:94077, J:325350)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
