The transgene contains the CAG promoter driving ubiquitous expression of the mouse sequence with the amino acid substitution of tyrosine to alanine at position 61 (Y61A in uniport Q80WM9; also known as the Y23A mutation). Lines 22 was generated. (J:304481)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count