A gene-targeting vector was generated containing the promoter and exon 1, intron 1, part of exon 2, part of exon 3, intron 3, and exon 4 of the Adm gene upstream of a BamH1 site and a neomycin resistance cassette. The finale allele lacks the coding sequence for the proadrenomedullin N-terminal 20 peptide. (J:286466)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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