The targeting construct inserted upstream of exon 2 an FRT-flanked neomycin resistance cassette with a 5 prime loxP site. Flp-mediated recombination removed the selection cassette. (J:316936)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count