The targeting construct inserted an F3-flanked puromycin resistance cassette with a 3 prime loxP site downstream of exon 7. Flp-mediated recombination removed the selection cassette. (J:316936)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count