CRISPR-targeting inserted a loxP site upstream of exon 4 and a rox-flanked neomycin resistance cassette with a 3 prime loxP site downstream of exon 4. Dre-mediated recombination removed the selection cassette and left exon 4 floxed. (J:312681)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count